I've been hurting myself trying to climb some of the mtn roads around Boulder, so decided to look into getting a compact crank. Due to some limitations of my bike, it was recommended I go with a different rear cassette instead. So I replaced my 11/23 with a 12/27, giving me a fair amount more low-end without too much loss on the high-end. Still running the 53/39 up front.
It's been a couple rides on the new gearing and so far it was definitely the right choice. I'm looking forward to the next ride on Sunday... I'm sure there will be a few big climbs on the route.